Tuesday, October 21, 2008

CJC 1295 with GHRP-6 and Hurezine A



The CJC-1295 & the total 24 hour dosing of GHRP-6 together comprise a single comparison with exogenic GH administration.I would not inject CJC 3X a day alone. But, in conjunction with GHRP-6, it makes sense. I believe 2mg a week is optimal for body building, less for anti-aging purposes. You are correct, CJC does bond for a long time, and if I was only to use CJC, I would use it 2X a week.CJC-1295 is a long-lasting analog of GHRH and therefore only twice a week dosing is needed to keep GH levels elevated. GHRP-6 (all the GHRPs) as soon as they are injected creates a 2 hour pulse of GH release.Administering both GHRP-6 (or any GHRP) and GHRH together synergistically increases that newly created pulse. GHRP-6 creates a big pulse of GH but GHRP-6 + GHRH creates a much bigger pulse of GH.I can't speak from experience, just from what I have read. Attempting to maximize the total amount of GH release over a 24 hour period I think you would want both GHRH chronically elevated and several GH pulses amplified.CJC-1295 chronically elevates GHRH without desensitizing or creating a waning GH release profile. This raises the troughs of GH (i.e. GH remains elevated & consequently so does liver-synthesized IGF-1). Elevated levels of IGF-1 have been shown to contribute to growth.GHRH + GHRPs administered together synergistically amplify a two hour pulse. Pulsation had been determined to be highly necessary for tissue growth. The studies do show that some GHRPs increasingly exert an effect up to about 400mcg (or 4mcg/kg). However adding more than 100mcg (1mcg/kg) of GHRH did not add to the synergy.Optimally you could dose 100mcg of CJC-1295 w/ 100-400mcg of GHRP in the morning (on an empty stomach 25 minutes before eating); again in the afternoon/Pre WO; finally just before bed.That protocol would create a weekly total of CJC-1295 of 2.1 mgs.There is benefit to adding more CJC-1295 but this will only increase Base GH levels & IGF-1 levels not pulse amplitude. The CJC-1295 clinical trial demonstrated that the CJC-1295 dose (aprox. 2.1 mgs) could be doubled, tripled even quadrupled and exert ever increasing positive elevations of GH & IGF-1 levels.It doesn't matter how/when you dose the extra CJC-1295 (i.e. you will dose 100mcg 3x per day w/ GHRP and the remaining CJC-1295 as is convenient).You could administer the extra CJC-1295 w/ the daily CJC/GHRP doses or twice a week in two large doses.As non-diseased aging adults our pituitary gland continues to possess the ability to secrete large amounts of GH (well above what is youthfully normal). Obviously there is a limit and this limit is arrived at in part by the negative feedback signals. Optimally dosing GHRH (analog CJC-1295) & GHRPs (GHRP-6, GHRP-2, Hexarelin, Ipamorelin) can likely achieve a GH releasing profile similar to and substitute for mid-high level exogenic dosing of Growth Hormone (GH).GHRP-6 has a finite life in blood plasma. Like all peptides it is subject to enzymatic degradation. Once administered it exerts its effects for a couple of hours before all of the peptide is broken down into amino acids or amino acid "strings" incapable of exerting an effect. They are in effect "digested".That effect that GHRP-6 exerts is basically "asking the pituitary to release more growth hormone & having the pituitary comply with the request". After GHRP-6 dies, so dies its request.


BEFORE you add in the Huperzine A or any other somatostatin inhibitor, use the CJC-1295 for a month first. That way you can better judge the difference of adding the Huperzine, and you can also see how CJC itself effects your body and compare various dosages to find what your body responds to best.THEN you should add the Huperzine A and play around with its dosage (start small, workup as you get comfortable), and also play around with the CJC dosage at the same time too.Good luck. You'll love the stuff. Its also awesome you only need inject it once or twice a week, keeps you from feeling like a pin cushion. Don’t combine the Huperzine A with it when you first start, because then you don’t know how the CJC by itself effects you, and if you experience wanted side effect, you wont know if its the CJC causing it or the Huperzine A. Whereas if you do CJC by itself for a month first, then add Huperzine, you can better identify what is causing a particular side effect.

33 comments:

Toby said...

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Hi this is great and tobee thanks for the info. GHRP-6 is just amazing and I've been using it for about a month now and it's just very effective.

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Anonymous said...

Hello PJ
The paragraph on Hurezine A is interesting. Can you tell me what effects are expected with the introduction of Hurezine A.

Interesting blog - tks

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Waldo said...

Can someone please help me with recommending some dosages and what to take? im 22 and want to get bigger (not water weight). I want to build muscle but stay lean. I have CJC and IGF, was also thinking about hitting prop and anathate. Any suggestions would be greaty apreciated?

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The CJC-1295 & the total 24 hour dosing of GHRP-6 together comprise a single comparison with exogenic GH administration.

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The CJC-1295 & the total 24 hour dosing of GHRP-6 together comprise a single comparison with exogenic GH administration.I would not inject CJC 3X a day alone.

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Unknown said...

Thank you for the advice on how much to take a week for body building. I am trying to build muscle, but I would like to speed the process up. Does anyone have any suggestions on workouts I can do while I am using this?

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